HCID 22285054, compound → HCID 22285066, compound

HRID 1061884Notes

Reaction equation

HRID 1061884 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]2[C:15](=[CH:16][CH:17]=1)[C:8]1[CH:9](OC)[O:10][C:11](=[O:12])[C:7]=1[CH:6]=[CH:5]2.CO.[CH3:20][NH2:21]>C1COCC1>[Br:1][C:2]1[CH:17]=[CH:16][C:15]2[C:8]3[CH:9]([OH:10])[N:21]([CH3:20])[C:11](=[O:12])[C:7]=3[CH:6]=[CH:5][C:4]=2[CH:3]=1

Participants

4

Reactant 2

HCID 22285054HCID 22285054, compoundHCID 57454252Monomethylamine methanol

Product 1

HCID 22285066HCID 22285066, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

7-Bromo-1-methoxynaphtho[1,2-c]furan-3(1H)-one (1.03 g) was dissolved in THF (10 mL), and 40% methylamine methanol solution (10 mL) was added. The reaction mixture was stirred at room temperature for 1 hr., and the solvent was evaporated to give the title compound (1.03 g) as pale-yellow crystals.

Workup

  1. custom, and the solvent was evaporated

Sources & evidence

ORD record
ord-21300f5ad9274f81b97374f033624a5a
Source dataset
uspto-grants-2005_11
Patent number
US06960586B2

Reaction notes

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