Potassium Bromide → Benzenesulfonamide

HRID 1063962Notes

Reaction equation

HRID 1063962 reaction equation
Cl[C:2]1[CH:7]=[CH:6][C:5]([S:8]([N:11](C2C=C(Cl)C=CC=2Cl)[C@H](C)CCN2CCCCC2CS(C)(=O)=O)(=[O:10])=[O:9])=[CH:4][CH:3]=1.ClC1C=CC(S(N(C2C=C(Cl)C=CC=2Cl)[C@H](C)CCBr)(=O)=O)=CC=1.[K+].[Br-]>>[C:5]1([S:8]([NH2:11])(=[O:10])=[O:9])[CH:6]=[CH:7][CH:2]=[CH:3][CH:4]=1

Participants

4

Reactant 3

HCID 253877Potassium BromideHCID 23401651HCID 23401651, compoundHCID 54024567HCID 54024567, compound

Product 1

HCID 7370BenzenesulfonamideYield 6%

Procedure

4-chloro-N-2,5-dichlorophenyl)-N-3-(2-carboxymethyl-3-thiazolidinyl)-1(R)-methylpropyl)-benzenesulfonamide was prepared analogous to 4-chloro-N-(2,5-dichlorophenyl)-N-(3-(2-((methylsulfonyl)methyl)-1-piperidinyl)-1(R)-methylpropyl)benzenesulfonamide by reacting 4-chloro-N-[2,5-dichlorophenyl]-N-[(R)-1-methyl-3-bromopropyl]benzenesulfonamide with 2-carboxymethyl-3-thiazolidine. Yield=6%; White powder: IR (KBr) 1747, 1467, 1352, 1166, 1094, 622 cm−1; MS (ESI+), 537 (M+H)+.

Sources & evidence

ORD record
ord-63111a8559904ba1a0a067130cd39e53
Source dataset
uspto-grants-2005_11
Patent number
US06967196B1

Reaction notes

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