反应详情

3,4,5,6-tetrahydrophthalic anhydride (16.0 g) and 2-fluoro-4-bromoaniline (20.0 g) were added to acetone (100 ml) and, after stirring at 40°-45° C. for 2 hours, the mixture was concentrated to dryness under reduced pressure. The resultant crystals were washed with n-hexane. Yield 30.3 g.; m.p. 98°-99° C.

1. concentrationthe mixture was concentrated to dryness under reduced pressure
2. washThe resultant crystals were washed with n-hexane