Benzyl Chloride → HCID 54109068, compound

HRID 1065380Notes

Reaction equation

HRID 1065380 reaction equation
[SH:1][CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:8]=[C:9]2[C:14](=[CH:15][CH:16]=1)[NH:13][C:12](=[O:17])[CH2:11][CH2:10]2.C(=O)([O-])[O-].[K+].[K+].[CH2:24](Cl)[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>CS(C)=O.O>[CH2:24]([S:1][CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:8]=[C:9]2[C:14](=[CH:15][CH:16]=1)[NH:13][C:12](=[O:17])[CH2:11][CH2:10]2)[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1

Participants

6

Reactant 3

HCID 7503Benzyl ChlorideHCID 11430Potassium CarbonateHCID 20540151HCID 20540151, compound

Product 1

HCID 54109068HCID 54109068, compound

Reagents, catalysts & solvents 2

HCID 679Dimethyl SulfoxideSolventHCID 962WaterSolvent

Procedure

A solution of 2.5 gm of 6-(4-mercapto-butoxy)-3,4-dihydro-carbostyril in 25 ml of dimethysulfoxide was mixed whilst stirring with 1.4 gm of potassium carbonate and subsequently with 1.3 ml of benzyl chloride. After stirring for 15 hours at room temperature, the reaction mixture was diluted with 200 ml of water, and the precipitated oily substance was separated and recrystallized from ethyl acetate.

Workup

  1. customthe precipitated oily substance was separated
  2. customrecrystallized from ethyl acetate

Sources & evidence

ORD record
ord-8d428df801954e0898cf362ca6e841ec
Source dataset
uspto-grants-1982_05
Patent number
US04329347

Reaction notes

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