3,3-Diphenylpropylamine → HCID 178527190, compound

HRID 1066121Notes

Reaction equation

HRID 1066121 reaction equation
Cl[C:2]1[NH:7][C:6]2[CH:8]=[CH:9][C:10]([Cl:12])=[CH:11][C:5]=2[S:4](=[O:14])(=[O:13])[N:3]=1.[C:15]1([CH:21]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[CH2:22][CH2:23][NH2:24])[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[Cl:12][C:10]1[CH:9]=[CH:8][C:6]2[NH:7][C:2]([NH:24][CH2:23][CH2:22][CH:21]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)=[N:3][S:4](=[O:14])(=[O:13])[C:5]=2[CH:11]=1

Participants

3

Reactant 2

HCID 796983,3-DiphenylpropylamineHCID 127001053,7-dichloro-2H-1,2,4-benzothiadiazine 1,1-dioxide

Product 1

HCID 178527190HCID 178527190, compound

Procedure

Starting from 3,7-dichloro-4H-1,2,4-benzothiadiazine 1,1-dioxide (300 mg; 1.19 mmol) and 3,3-diphenylpropylamine (1.5 g; 7.1 mmol) with the use of same procedure as in example 21 300 mg (59%) of the title compound was prepared; 1H-NMR (DMSO-d6) ppm; 10.7 (s, 1H, NH), 7.68 (d, 1H, H-8), 7.60 (dd, 1H, H-5), 7.25 (m, 11H, ), 4.1 (t, 1H, CH), 3.11 (q, 2H, CH2), 2.35 (q, 2H, CH2); MS:EI/70eV: 425 (M+), 245, 193, 180, 165, 152, 115.

Sources & evidence

ORD record
ord-ee53bd4c7b4d4a1baf35a037a3f0ef6f
Source dataset
uspto-grants-2001_06
Patent number
US06242443B1

Reaction notes

Loading…