Isopropyl Isothiocyanate → HCID 178456955, compound

HRID 1066138Notes

Reaction equation

HRID 1066138 reaction equation
[NH2:1][C:2]1[C:7]([Br:8])=[CH:6][C:5]([Br:9])=[CH:4][C:3]=1[S:10]([NH2:13])(=[O:12])=[O:11].[CH:14]([N:17]=[C:18]=S)([CH3:16])[CH3:15]>C(OCC)(=O)C>[Br:8][C:7]1[C:2]2[NH:1][C:18]([NH:17][CH:14]([CH3:16])[CH3:15])=[N:13][S:10](=[O:12])(=[O:11])[C:3]=2[CH:4]=[C:5]([Br:9])[CH:6]=1

Participants

4

Reactant 2

HCID 75263Isopropyl IsothiocyanateHCID 12013962-Amino-3,5-dibromobenzenesulfonamide

Product 1

HCID 178456955HCID 178456955, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The title compound was prepared from 2-amino-3,5-dibromobenzenesulfonamide and isopropyl isothiocyanate by a method analogous to the one described in Example 4; m.p. 306-311° C. (ethyl acetate); 1H-NMR (DMSO-d6): δ 1.19 (d, 6H, CH(CH3)2), 3.90 (m, 1H, CH(CH3)2), 7.82 (d, 1H, ArH), 7.92 (br.d, 1H, NH), 8.16 (d, 1H, ArH), 9.65 (br.s, 1H, NH); MS: m/e 395/397/399 (M+); (C10H11N3Br2O2S1) calc. C, 30.25; H, 2.79; N, 10.58; found C, 30.34; H, 2.77; N, 10.48.

Sources & evidence

ORD record
ord-641f7dcce0804bada701c7ee7f310d98
Source dataset
uspto-grants-2001_06
Patent number
US06242443B1

Reaction notes

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