Allyl Isothiocyanate → HCID 178456967, compound

HRID 1066140Notes

Reaction equation

HRID 1066140 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[S:9]([NH2:12])(=[O:11])=[O:10].[CH2:13]([N:16]=[C:17]=S)[CH:14]=[CH2:15]>C(OCC)(=O)C>[CH2:13]([NH:16][C:17]1[NH:1][C:2]2[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=2[S:9](=[O:11])(=[O:10])[N:12]=1)[CH:14]=[CH2:15]

Participants

4

Reactant 2

HCID 5971Allyl IsothiocyanateHCID 777902-Amino-4-chlorobenzenesulphonamide

Product 1

HCID 178456967HCID 178456967, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The title compound was prepared from 2-amino-4-chlorobenzenesulfonamide and allyl isothiocyanate by a method analogous to the one described in Example 4; m.p. 284-286° C. (ethyl acetate); 1H-NMR (DMSO-d6): δ 3.88 (distorted t, 2H, NHCH2), 5.1-5.3 (m, 2H, ═CH2), 5.78-6.0 (m, 1H, ═CH), 7.22-7.35 (m, 2H, ArH), 7.50 (br.t, 1H, NH), 7.69 (d, 1H, ArH), 10.73 (br.s, 1H, NH); MS: m/e 271/273 (M+); (C10H10N3Cl1O2S1) calc. C, 44.20; H, 3.71 N, 15.46; found C, 44.10; H, 3.79; N, 15.32.

Sources & evidence

ORD record
ord-31af34ec01ad45b38e3386e1edf56de2
Source dataset
uspto-grants-2001_06
Patent number
US06242443B1

Reaction notes

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