Acetate → Tert-butyl 3-(6-methyl-3-pyridinyl)prop-2-enoate

HRID 106656Notes

Reaction equation

HRID 106656 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH3:8])[n:6][cH:7]1.[C:9]([CH:10]=[CH2:11])(=[O:12])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17].[CH3:18][CH2:19][N:20]([CH2:21][CH3:22])[CH2:23][CH3:24].[CH3:26][N:27]1[CH2:28][CH2:29][CH2:30][C:31]1=[O:32].[O-:34][C:35]([CH3:36])=[O:37].[O-:38][C:39]([CH3:40])=[O:41].[OH2:25].[Pd+2:33]>>[c:2]1([CH:11]=[CH:10][C:9](=[O:12])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[cH:3][cH:4][c:5]([CH3:8])[n:6][cH:7]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 962WaterHCID 8471TriethylamineHCID 13387N-methyl-2-pyrrolidoneHCID 15458tert-Butyl acrylateHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 12010205-Bromo-2-methylpyridine

Product 1

HCID 66872020Tert-butyl 3-(6-methyl-3-pyridinyl)prop-2-enoate

Sources & evidence

ORD record
ord-2606af889a41428b9e94aeacdf2513f0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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