Ethylene carbonate → HCID 21196994, compound

HRID 1067052Notes

Reaction equation

HRID 1067052 reaction equation
O[C:2]1[CH:14]=[CH:13][C:12]2[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5](=[O:15])[C:4]=2[CH:3]=1.C1(=O)[O:20][CH2:19][CH2:18][O:17]1>C(N(CC)CC)C>[OH:17][CH2:18][CH2:19][O:20][C:3]1[C:4]2[C:5](=[O:15])[C:6]3[C:11](=[CH:10][CH:9]=[CH:8][CH:7]=3)[C:12]=2[CH:13]=[CH:14][CH:2]=1

Participants

4

Reactant 2

HCID 7303Ethylene carbonateHCID 813862-Hydroxyfluoren-9-one

Product 1

HCID 21196994HCID 21196994, compoundYield 63%

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

Following the procedure described in Example 29, 2-hydroxyfluoren-9-one (Aldrich) was reacted with ethylene carbonate and triethylamine to obtain 2-hydroxyethoxyfluoren-9-one (63% yield), with a melting point of 118-119° C. The title compound, with a melting point of 131.5-133° C., was obtained in 96% yield by the previously described DBU-catalyzed reaction with VDM in heptane.

Sources & evidence

ORD record
ord-f464ec1a2fd64ef1945d491f3ed2eb81
Source dataset
uspto-grants-2001_06
Patent number
US06245922B1

Reaction notes

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