Ethylene carbonate → HCID 53818460, compound

HRID 1067053Notes

Reaction equation

HRID 1067053 reaction equation
[OH:1][CH2:2][CH2:3]OC1C2C(=O)C3C(=CC=CC=3)SC=2C=CC=1.[OH:20][C:21]1[CH:30]=[C:29]2[C:24]([C:25](=[O:37])[CH:26]=[C:27]([C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=3)[O:28]2)=[CH:23][CH:22]=1.C1(=O)OCCO1>C(N(CC)CC)C>[OH:1][CH2:2][CH2:3][O:20][C:21]1[CH:30]=[C:29]2[C:24]([C:25](=[O:37])[CH:26]=[C:27]([C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=3)[O:28]2)=[CH:23][CH:22]=1

Participants

5

Reactant 3

HCID 7303Ethylene carbonateHCID 52818947-HydroxyflavoneHCID 21196993HCID 21196993, compound

Product 1

HCID 53818460HCID 53818460, compoundYield 83%

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

In an analogous fashion to 2-hydroxyethoxythioxanthone in Example 29, 7-hydroxyflavone (Aldrich) was reacted with ethylene carbonate and triethylamine to obtain 7-hydroxyethoxyflavone (83% yield). This product was dissolved in THF. One equivalent of VDM and several drops of DBU were added. The reaction mixture was stirred overnight.

Sources & evidence

ORD record
ord-9945c887382e4f499e597f1a16547ba7
Source dataset
uspto-grants-2001_06
Patent number
US06245922B1

Reaction notes

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