Urea → 4-Nitroaniline

HRID 1067056Notes

Reaction equation

HRID 1067056 reaction equation
[CH:1]1[C:6]([NH2:7])=[CH:5][CH:4]=[C:3]([NH2:8])[CH:2]=1.N[C:10]([NH2:12])=[O:11].[N+:13]([C:16]1[CH:21]=[CH:20]C=[CH:18][CH:17]=1)([O-:15])=[O:14]>>[N:7]([C:6]1[CH:5]=[CH:4][C:3]([NH2:8])=[CH:2][CH:1]=1)=[O:11].[N+:13]([C:16]1[CH:21]=[CH:20][C:10]([NH2:12])=[CH:18][CH:17]=1)([O-:15])=[O:14]

Participants

5

Reactant 3

HCID 1176UreaHCID 7416NitrobenzeneHCID 7814P-Phenylenediamine

Product 2

HCID 74754-NitroanilineHCID 695744-Nitrosoaniline

Procedure

To achieve the above object, there is provided a method of preparing p-phenylenediamine including the steps of: reacting urea and nitrobenzene with a base in the presence of a polar solvent to yield 4-nitrosoaniline and 4-nitroaniline; and subsequently, diluting the resulting mixed solution in an alcohol and performing hydrogenation using a catalyst.

Workup

  1. customthere is provided

Sources & evidence

ORD record
ord-6f419591ec6b45079966fc970ae8a78a
Source dataset
uspto-grants-2001_06
Patent number
US06245943B1

Reaction notes

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