反应详情

A mixture of 9-chloro-1,2,3,4-tetrahydroacridine (6.18 g) and O-(2-fluorobenzyl)hydroxylamine hydrochloride (5.5 g) in 125 ml of n-propanol was heated at reflux for 20 hours. The reaction mixture was then added to an iced sodium bicarbonate solution and extracted with ethyl acetate (3×). The combined organics were washed with water and dried (saturated NaCl, MgSO4).

1. temperaturewas heated
2. temperatureat reflux for 20 hours
3. extractionextracted with ethyl acetate (3×)
4. washThe combined organics were washed with water
5. dry with materialdried (saturated NaCl, MgSO4)