Trifluoroacetic acid → Acetyl trifluoroacetate

HRID 1068067Notes

Reaction equation

[F:1][C:2]([F:13])([F:12])[C:3]([O:5][C:6](=[O:11])[C:7](F)(F)F)=[O:4].C=C=O.FC(F)(F)C(O)=O>>[F:1][C:2]([F:13])([F:12])[C:3]([O:5][C:6](=[O:11])[CH3:7])=[O:4]

Participants

Reactant 3

HCID 6422Trifluoroacetic acid

HCID 9845Trifluoroacetic anhydride

HCID 10038Ketene

Product 1

HCID 12752924Acetyl trifluoroacetate

Procedure

Process for the production of trifluoroacetic anhydride (TFAA) which comprises contacting ketene and trifluoroacetic acid (TFA) to produce a mixed anhydride, acetyl trifluoroacetate (Ac-TFA) and subjecting the mixed anhydride to reactive distillation to produce a lower boiling product comprising TFAA and a higher boiling product comprising acetic anhydride (AC2O).

Sources & evidence

ORD record: ord-05b7aefeca9e4175a359d1cd849d67cb
Source dataset: uspto-grants-2001_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06248923B1

Reaction notes

Loading…