Allyl bromide → HCID 21193027, compound

HRID 1068145Notes

Reaction equation

HRID 1068145 reaction equation
[NH:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[CH:10]1[CH2:15][CH2:14][N:13]([C:16](=[O:18])[CH3:17])[CH2:12][CH2:11]1.[H-].[Na+].[CH2:21](Br)[CH:22]=[CH2:23]>CN(C=O)C>[CH2:23]([N:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[CH:10]1[CH2:11][CH2:12][N:13]([C:16](=[O:18])[CH3:17])[CH2:14][CH2:15]1)[CH:22]=[CH2:21]

Participants

5

Reactant 3

HCID 7841Allyl bromideHCID 24758Sodium hydrideHCID 21193130HCID 21193130, compound

Product 1

HCID 21193027HCID 21193027, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The title compound was prepared from 1-(4-(1-H-benzoimidazol-2-yl)-piperidin-1-yl)ethanone (from Step A), sodium hydride, allyl bromide and DMF.

Sources & evidence

ORD record
ord-fb53e85d37f94bc9bd01c9dd380fcdc3
Source dataset
uspto-grants-2001_06
Patent number
US06248755B1

Reaction notes

Loading…