Hydrochloric Acid → HCID 86754055, compound

HRID 1068498Notes

Reaction equation

HRID 1068498 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([CH2:14][N:15]2[C:19]([CH2:20][C:21]3[CH:26]=[CH:25][C:24]([C:27]#[N:28])=[CH:23][CH:22]=3)=[CH:18][N:17]=[CH:16]2)[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:29]>CCOC(C)=O>[ClH:29].[ClH:29].[NH:8]1[CH2:13][CH2:12][CH:11]([CH2:14][N:15]2[C:19]([CH2:20][C:21]3[CH:22]=[CH:23][C:24]([C:27]#[N:28])=[CH:25][CH:26]=3)=[CH:18][N:17]=[CH:16]2)[CH2:10][CH2:9]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 21193368HCID 21193368, compound

Product 1

HCID 86754055HCID 86754055, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

Into a solution of the product from step C (0.843 g, 2.21 mmol) in EtOAc (200 mL) at 0° C. was bubbled HCl gas. After 10 minutes the solvent was evaporated in vacuo to afford the title compound as a foam.

Workup

  1. customAfter 10 minutes the solvent was evaporated in vacuo

Sources & evidence

ORD record
ord-593438d953ad4b35a0fbc5031a7ca3ce
Source dataset
uspto-grants-2001_06
Patent number
US06248756B1

Reaction notes

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