Hydrochloric Acid → HCID 21190190, compound

HRID 1068693Notes

Reaction equation

HRID 1068693 reaction equation
[F:1][C:2]([F:24])([F:23])[S:3]([NH:6][CH2:7][CH2:8][CH2:9][CH2:10][N:11]1[CH2:21][C:20]2[N:22]3[C:13](=[CH:14][N:15]=[C:16]3[CH:17]=[CH:18][CH:19]=2)[CH2:12]1)(=[O:5])=[O:4].[ClH:25]>C(O)C>[ClH:25].[ClH:25].[F:23][C:2]([F:1])([F:24])[S:3]([NH:6][CH2:7][CH2:8][CH2:9][CH2:10][N:11]1[CH2:21][C:20]2[N:22]3[C:13](=[CH:14][N:15]=[C:16]3[CH:17]=[CH:18][CH:19]=2)[CH2:12]1)(=[O:4])=[O:5]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 21190191HCID 21190191, compound

Product 1

HCID 21190190HCID 21190190, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 3.21 g (8.87 mmol) of 4,5-dihydro-4-[4-(trifluoromethanesulfonamido)butan-1-yl]-3H-1,4,8b-triazaacenaphthylene in 10 ml of ethanol was added 2.0 ml of 12N HCl. The mixture was sufficiently blended. The solvent was distilled off under reduced pressure to leave 3.86 g of the desired compound (100%, colorless amorphous).

Workup

  1. distillationThe solvent was distilled off under reduced pressure

Sources & evidence

ORD record
ord-928d63c940694c9cb56f88991a63772f
Source dataset
uspto-grants-2001_06
Patent number
US06251905B1

Reaction notes

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