HCID 86757044, compound → HCID 56670621, compound

HRID 1069026Notes

Reaction equation

HRID 1069026 reaction equation
CC1(C)[O:6][CH:5]2[CH:7]([N:12]3[C:16]4[N:17]=[C:18]([S:31][CH2:32][CH2:33][CH3:34])[N:19]=[C:20]([NH:21][CH:22]5[CH2:24][CH:23]5[C:25]5[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=5)[C:15]=4[N:14]=[N:13]3)[CH2:8][CH:9]([CH2:10][OH:11])[CH:4]2[O:3]1>CO.Cl>[OH:11][CH2:10][CH:9]1[CH2:8][CH:7]([N:12]2[C:16]3[N:17]=[C:18]([S:31][CH2:32][CH2:33][CH3:34])[N:19]=[C:20]([NH:21][CH:22]4[CH2:24][CH:23]4[C:25]4[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=4)[C:15]=3[N:14]=[N:13]2)[CH:5]([OH:6])[CH:4]1[OH:3]

Participants

4

Reactant 1

HCID 86757044HCID 86757044, compound

Product 1

HCID 56670621HCID 56670621, compound

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 887MethanolSolvent

Procedure

A solution of the product from step (a) (18.5 g) in methanol (1 L) and 2N HCl (150 ml) was stirred at room temperature for 2 hours and concentrated in vacuo. Water (500 ml) was added and the product was collected by filtration and dried (16.7 g).

Workup

  1. concentrationconcentrated in vacuo
  2. additionWater (500 ml) was added
  3. filtrationthe product was collected by filtration
  4. customdried (16.7 g)

Sources & evidence

ORD record
ord-a88e762b993446a48078ee81500ae47e
Source dataset
uspto-grants-2001_06
Patent number
US06251910B1

Reaction notes

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