Tetrahydrofuran → 3-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-isothiazole-5-carboxylic acid methyl ester

HRID 106904Notes

Reaction equation

HRID 106904 reaction equation
[CH2:56]1[O:57][CH2:58][CH2:59][CH2:60]1.[CH3:15][O:16][C:17](=[O:18])[c:19]1[cH:20][c:21]([OH:24])[n:22][s:23]1.[CH3:1][c:2]1[c:3]([CH2:13][OH:14])[c:4](-[c:7]2[cH:8][cH:9][cH:10][cH:11][cH:12]2)[n:5][o:6]1.[O:44]=[C:45]([O:46][CH2:47][CH3:48])[N:49]=[N:50][C:51]([O:52][CH2:53][CH3:54])=[O:55].[c:25]1([P:26]([c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)[cH:39][cH:40][cH:41][cH:42][cH:43]1>>[CH3:1][c:2]1[c:3]([CH2:13][O:14][c:21]2[cH:20][c:19]([C:17]([O:16][CH3:15])=[O:18])[s:23][n:22]2)[c:4](-[c:7]2[cH:8][cH:9][cH:10][cH:11][cH:12]2)[n:5][o:6]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 220568ethyl N-ethoxycarbonyliminocarbamateHCID 2776149(5-Methyl-3-phenyl-1,2-oxazol-4-yl)methanolHCID 178498604HCID 178498604, compound

Product 1

HCID 674921363-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-isothiazole-5-carboxylic acid methyl ester

Sources & evidence

ORD record
ord-6ce94e9b31d64455a00ba8546016963b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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