反应详情

A mixture of 1 mL of 1M BBr3/methylene chloride and 0.24 g (0.79 mmol) of 1-hexyl-5-methoxy-2-methyl-1H-indole-3-acetamide in 20 mL of methylene chloride as stirred for 16 hours, diluted with ethyl acetate and washed twice with water. The solution was dried (Na2SO4) and the solvent removed at reduced pressure to give 0.23 g of crude 1-hexyl-5-hydroxy-2-methyl-1H-indole-3-acetamide.

1. washwashed twice with water
2. dry with materialThe solution was dried (Na2SO4)
3. customthe solvent removed at reduced pressure