Pyridine → HCID 868381, compound

HRID 1070672Notes

Reaction equation

HRID 1070672 reaction equation
[C:1](Cl)(=[O:3])[CH3:2].[OH:5][C:6]1[C:15]([OH:16])=[CH:14][C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH:7]=1.N1C=CC=CC=1>C(OCC)(=O)C>[OH:5][C:6]1[C:15]([O:16][C:1](=[O:3])[CH3:2])=[CH:14][C:13]2[C:8]([CH:7]=1)=[CH:9][CH:10]=[CH:11][CH:12]=2

Participants

5

Reactant 3

HCID 1049PyridineHCID 6367Acetyl chlorideHCID 70912,3-Dihydroxynaphthalene

Product 1

HCID 868381HCID 868381, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

Acetylchloride (0.71 ml) was added to a solution of 2,3-dihydroxynaphthalene (1.6 g) and pyridine (0.81 ml) in ethyl acetate (20 ml) at 0° C. The mixture was stirred for few hours at room temperature and then washed with water, dried and evaporated to dryness. The crude product was recrystallized from ether. Yield: 0.52 g.

Workup

  1. washwashed with water
  2. customdried
  3. customevaporated to dryness
  4. customThe crude product was recrystallized from ether

Sources & evidence

ORD record
ord-593b849f30a1492b9782085ca83d665f
Source dataset
uspto-grants-2005_06
Patent number
US06903114B2

Reaction notes

Loading…