Malononitrile → HCID 3773318, compound

HRID 1071870Notes

Reaction equation

HRID 1071870 reaction equation
[Br:1][C:2]1[C:3]([O:12][CH3:13])=[C:4]([O:10][CH3:11])[CH:5]=[C:6]([CH:9]=1)[CH:7]=O.[C:14](#[N:18])[CH2:15][C:16]#[N:17].N1CCCCC1>C(O)C>[CH3:11][O:10][C:4]1[CH:5]=[C:6]([CH:9]=[C:2]([Br:1])[C:3]=1[O:12][CH3:13])[CH:7]=[C:15]([C:14]#[N:18])[C:16]#[N:17]

Participants

5

Reactant 3

HCID 8010MalononitrileHCID 8082PiperidineHCID 813793-Bromo-4,5-dimethoxybenzaldehyde

Product 1

HCID 3773318HCID 3773318, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a mixture of 5-bromoveratraldehyde (245 mg, 1 mmol) and malononitrile (66 mg, 1 mmol) in ethanol was added piperidine (0.1 ml, 1 mmol). The mixture was stirred at room temperature for 15 min to give the product 3,4-dimethoxy-5-bromobenzylidenemalononitrile as a yellow precipitate.

Sources & evidence

ORD record
ord-724c91b018b448b0b40617583f3c1803
Source dataset
uspto-grants-2005_06
Patent number
US06906203B1

Reaction notes

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