Hydrochloric Acid → HCID 22390693, compound

HRID 1071967Notes

Reaction equation

HRID 1071967 reaction equation
[N:1]([CH2:4][CH2:5][C:6]1[CH:13]=[CH:12][C:9]([C:10]#[N:11])=[CH:8][CH:7]=1)=[N+:2]=[N-:3].Cl.[CH3:15][CH2:16][OH:17]>>[N:1]([CH2:4][CH2:5][C:6]1[CH:13]=[CH:12][C:9]([C:10](=[NH:11])[O:17][CH2:16][CH3:15])=[CH:8][CH:7]=1)=[N+:2]=[N-:3]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 22390712HCID 22390712, compound

Product 1

HCID 22390693HCID 22390693, compound

Procedure

A solution of 4-(2-azidoethyl)benzonitrile (2.0 g, 11.62 mmol) in EtOH (50 ml) at 0° C. was saturated with HCl(g). Reaction mixture was allowed to warm to room temperature and stirred overnight. Concentration of the crude reaction mixture gave ethyl 4-(2-azidoethyl)benzenecarboximidoate which was used without further purification.

Workup

  1. customat 0° C.
  2. customReaction mixture
  3. customConcentration of the crude reaction mixture

Sources & evidence

ORD record
ord-f78702cf7496400e895737c01455bf63
Source dataset
uspto-grants-2005_06
Patent number
US06908921B2

Reaction notes

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