Ethanol → HCID 22387303, compound

HRID 1072738Notes

Reaction equation

HRID 1072738 reaction equation
C([O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]2[N:16]([C:21]3[CH:26]=[CH:25][C:24](OCCCCCCCCCC)=CC=3)[C:17]([CH3:20])=[CH:18][CH:19]=2)=[CH:11][CH:10]=1)C1C=CC=CC=1.[CH2:38]([OH:40])[CH3:39]>O1CCCC1.[C].[Pd]>[CH2:38]([O:40][C:26]1[CH:25]=[CH:24][C:25]([CH2:26][CH2:21][N:16]2[C:17]([CH3:20])=[CH:18][CH:19]=[C:15]2[C:12]2[CH:11]=[CH:10][C:9]([OH:8])=[CH:14][CH:13]=2)=[CH:24][CH:21]=1)[CH2:39][CH2:19][CH2:15][CH2:12][CH2:11][CH2:10][CH2:9][CH2:14][CH3:13]

Participants

5

Reactant 2

HCID 702EthanolHCID 22387316HCID 22387316, compound

Product 1

HCID 22387303HCID 22387303, compoundYield 93.5%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 8028TetrahydrofuranSolvent

Procedure

To a solution of 2-(4-benzyloxyphenyl)-1-(4-decyloxyphenyl)-5-methyl-1H-pyrrole (1.70 g, 3.43 mmol) in ethanol (60 ml) and tetrahydrofuran (30 ml) was added 10% palladium carbon (200 mg) and the mixture was stirred for 4 hours under hydrogen atmosphere. The insoluble matter was filtered out and the filtrate was concentrated to give the object compound as an oily substance. 1.30 g (yield: 93.5%)

Workup

  1. filtrationThe insoluble matter was filtered out
  2. concentrationthe filtrate was concentrated
  3. customto give the object compound as an oily substance

Sources & evidence

ORD record
ord-3520b9ffeb1344818a66f30bc9efee13
Source dataset
uspto-grants-2005_06
Patent number
US06911468B2

Reaction notes

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