反应详情

温度

120 °C

A mixture of p-aminobenzonitrile (2.00 g), Meldrum's acid (2.56 g), ethyl orthoformate (2.76 g) and ethanol (10 ml) was heated at 120° C. (bath temperature) to evaporate the ethanol. Ethyl acetate was added to the obtained orange solid. The solid was pulverized, collected by filtration and washed with ethyl acetate to give the object compound (3.28 g) as a white powder.

1. customto evaporate the ethanol
2. additionEthyl acetate was added to the obtained orange solid
3. filtrationcollected by filtration
4. washwashed with ethyl acetate