Triphenylphosphine → HCID 10536182, compound

HRID 1073082Notes

Reaction equation

HRID 1073082 reaction equation
[CH:1]([N:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[N+:7]([O-])=[C:6]([OH:15])[C:5]1=[O:16])([CH3:3])[CH3:2].C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>CN(C)C=O>[CH:1]([N:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[NH:7][C:6](=[O:15])[C:5]1=[O:16])([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 11776TriphenylphosphineHCID 178456567HCID 178456567, compound

Product 1

HCID 10536182HCID 10536182, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A solution of 3,4-dihydro-4-isopropyl-2-hydroxy-3-oxo-quinoxaline-1-oxid (15.5 g, 0.07 mole) and triphenylphosphine (26.2 g, 0.1 mole) in dimethylformamide (DMF) (100 ml) was stirred at 120° C. for 12 hours, whereafter the solvent was evaporated in vacuo. The residue was stirred in methylene chloride (150 ml) whereby the formed triphenyl phosphine oxid was dissolved. The product was then collected as pale crystals by filtration followed by wash with methylene chloride. M.p. 227°-228° C.

Workup

  1. customwas evaporated in vacuo
  2. dissolutionwas dissolved
  3. filtrationThe product was then collected as pale crystals by filtration
  4. washby wash with methylene chloride

Sources & evidence

ORD record
ord-30039d600f0340759b90c59b39f7f962
Source dataset
uspto-grants-1990_11
Patent number
US04968682

Reaction notes

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