Bromide ion → HCID 131716686, compound

HRID 1073265Notes

Reaction equation

HRID 1073265 reaction equation
[O:1]=[C:2]([C:14]1[CH:19]=[CH:18][C:17]([S:20][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)=[CH:16][CH:15]=1)[CH2:3][N+:4]12CN3CN(CN(C3)C1)C2.[Br-].[ClH:28]>C(O)C>[ClH:28].[NH2:4][CH2:3][C:2]([C:14]1[CH:19]=[CH:18][C:17]([S:20][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)=[CH:16][CH:15]=1)=[O:1]

Participants

5

Reactant 3

HCID 259Bromide ionHCID 313Hydrochloric AcidHCID 57239669HCID 57239669, compound

Product 1

HCID 131716686HCID 131716686, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a suspension of 3.53 g of 1-[2-oxo-2-[4(phenylthio)phenyl]ethyl]-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7 ]decane, bromide in 35 ml of ethanol was added 6 ml of concentrated hydrochloric acid. This mixture was stirred for 17 hours, then the solid was collected and washed with ethanol and ether. This solid was stirred with 15 ml of water at 0° C. for 50 minutes, then the solid was collected, washed with 20 ml of ice cold water and dried, giving 1.38 g of the desired compound as a white solid, mp 222°-224° C. (dec.).

Workup

  1. customthe solid was collected
  2. washwashed with ethanol and ether
  3. stirringThis solid was stirred with 15 ml of water at 0° C. for 50 minutes
  4. customthe solid was collected
  5. washwashed with 20 ml of ice cold water
  6. customdried

Sources & evidence

ORD record
ord-639bb6dba5a54305ba28edff672bce04
Source dataset
uspto-grants-1990_11
Patent number
US04968702

Reaction notes

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