4-Chloropyridine hydrochloride → HCID 14988281, compound

HRID 1073556Notes

Reaction equation

HRID 1073556 reaction equation
[C:1]([CH2:3][C:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[N:6]([NH2:13])[CH:5]=1)#[N:2].Cl.Cl[C:16]1[CH:21]=[CH:20][N:19]=[CH:18][CH:17]=1>C(O)(C)C>[C:1]([CH2:3][C:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[N:6]([NH:13][C:16]2[CH:21]=[CH:20][N:19]=[CH:18][CH:17]=2)[CH:5]=1)#[N:2]

Participants

4

Reactant 2

HCID 818524-Chloropyridine hydrochlorideHCID 14988296HCID 14988296, compound

Product 1

HCID 14988281HCID 14988281, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

The title compound was prepared from 3-cyanomethyl-1H-indol-1-amine and 4-chloropyridine hydrochloride in isopropanol at 90° C. for 6 hours in substantially the same manner as in Example 1, m.p. 80°-83° C.

Sources & evidence

ORD record
ord-8abacd852921482693ac580b76d43c54
Source dataset
uspto-grants-1990_11
Patent number
US04970218

Reaction notes

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