Ethanol → HCID 178466987, compound

HRID 1074125Notes

Reaction equation

HRID 1074125 reaction equation
[Na].[NH2:2][C:3]1[N+:8]([O-:9])=[C:7]([NH2:10])[CH:6]=[C:5](Cl)[N:4]=1.[CH2:12]([OH:14])[CH3:13]>>[NH2:2][C:3]1[N+:8]([O-:9])=[C:7]([NH2:10])[CH:6]=[C:5]([O:14][CH2:12][CH3:13])[N:4]=1

Participants

4

Reactant 3

HCID 702EthanolHCID 5360545SodiumHCID 178507684HCID 178507684, compound

Product 1

HCID 178466987HCID 178466987, compound

Conditions

Temperature
120 °C

Procedure

1.8 g of sodium are dissolved in 100 ml of ethanol. 10 g of 2,4-diamino-6-chloropyrimidine 3-oxide are added. The reaction mixture is refluxed until the starting material has disappeared and is heated to 120° C. in an autoclave for 7 hours. It is returned to ambient temperature and the insoluble material is filtered off and washed with ethanol.

Workup

  1. temperatureThe reaction mixture is refluxed until the starting material
  2. customis returned to ambient temperature
  3. filtrationthe insoluble material is filtered off
  4. washwashed with ethanol

Sources & evidence

ORD record
ord-57b93f5ca486432fb7248bec06435744
Source dataset
uspto-grants-1990_11
Patent number
US04973474

Reaction notes

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