Hydrochloric Acid → HCID 22155962, compound

HRID 1074204Notes

Reaction equation

HRID 1074204 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8][C:9]1[NH:10][CH:11]=[CH:12][N:13]=1.Cl>CO.C(O)C>[ClH:1].[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8][C:9]1[NH:13][CH:12]=[CH:11][N:10]=1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 150775002-[(2-Chlorophenyl)thio]-1H-imidazole

Product 1

HCID 22155962HCID 22155962, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 887MethanolSolvent

Procedure

A solution of the product from Example 33 in methanol was treated with an excess of hydrogen chloride in ethyl alcohol. The mixture was concentrated in vacuo and the residue triturated with ether and filtered. The solid was recrystallized from methanol/ether to give the product as colorless prisms, mp 189°-192° C. (sealed tube).

Workup

  1. concentrationThe mixture was concentrated in vacuo
  2. customthe residue triturated with ether
  3. filtrationfiltered
  4. customThe solid was recrystallized from methanol/ether
  5. customto give

Sources & evidence

ORD record
ord-d49466c87cf54f1ca4d630fe8988a6b2
Source dataset
uspto-grants-1990_11
Patent number
US04973599

Reaction notes

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