Triethylamine → 2-Methyl-N-[3-(triethoxysilyl)propyl]acrylamide
Reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][Si:5]([O:12][CH2:13][CH3:14])([O:9][CH2:10][CH3:11])[O:6][CH2:7][CH3:8].C(N(CC)CC)C.[C:22](Cl)(=[O:26])[C:23]([CH3:25])=[CH2:24]>C1(C)C=CC=CC=1>[C:22]([NH:1][CH2:2][CH2:3][CH2:4][Si:5]([O:12][CH2:13][CH3:14])([O:6][CH2:7][CH3:8])[O:9][CH2:10][CH3:11])(=[O:26])[C:23]([CH3:25])=[CH2:24]Participants
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 0 °C
Procedure
A solution of 3-aminopropyltriethoxysilane (20.0 g) in toluene (200 ml) was added to a 500 ml three neck flask equipped with magnetic stir bar, addition funnel, and nitrogen inlet. A total of 9.11 g of triethylamine was added to the solution and the solution was cooled to 0° C. in an ice bath. A total of 9.41 g of methacryloyl chloride was added dropwise to the reaction by the addition funnel at a rate such that the temperature did not exceed 5° C. The reaction was stirred overnight with gradual warming to room temperature. The reaction mixture was then washed 4 times with 200 ml of ice water, dried over magnesium sulfate and concentrated under vacuum. The yield was 38.4 percent and the reaction product was used without further purification.
Workup
- customequipped with magnetic stir bar, addition funnel, and nitrogen inlet
- customdid not exceed 5° C
- temperaturewith gradual warming to room temperature
- washThe reaction mixture was then washed 4 times with 200 ml of ice water
- dry with materialdried over magnesium sulfate
- concentrationconcentrated under vacuum
- customThe yield was 38.4 percent and the reaction product was used without further purification
Sources & evidence
- ORD record
- ord-e3795e7e93fd4cda865327ab99985853
- Source dataset
- uspto-grants-1990_11
- Patent number
- US04973680
Reaction notes
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