Sodium Sulfite → HCID 23713289, compound

HRID 1074220Notes

Reaction equation

HRID 1074220 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4](F)[N:3]=1.[S:9]([O-:12])([O-:11])=[O:10].[Na+:13].[Na+]>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([S:9]([O-:12])(=[O:11])=[O:10])[N:3]=1.[Na+:13]

Participants

3

Reactant 2

HCID 24437Sodium SulfiteHCID 739342,6-Difluoropyridine

Product 1

HCID 23713289HCID 23713289, compoundYield 10.5%

Procedure

In the same manner as in Example 1, 1.725 g (15 mmol) of 2,6-difluoropyridine and 2.27 g (18 mmol) of sodium sulfite were reacted at 170° C. for 5 hours. By conducting the same post-treatment as in Example 1, 0.315 g (10.5%) of sodium 2-fluoropyridine-6-sulfonate was obtained.

Sources & evidence

ORD record
ord-a65b0153209e4f5d8d14669fe7706b4b
Source dataset
uspto-grants-1990_11
Patent number
US04973697

Reaction notes

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