1,8-Dibromooct-1-yne → HCID 53878301, compound

HRID 1074510Notes

Reaction equation

HRID 1074510 reaction equation
Br[C:2]#[C:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][Br:10]>O1CCCC1>[Br:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][C:3]#[C:2][CH2:2][CH2:3][CH:4]=[CH:5][CH2:6][CH2:7][CH2:8][CH3:9]

Participants

3

Reactant 1

HCID 128311901,8-Dibromooct-1-yne

Product 1

HCID 53878301HCID 53878301, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

On the other hand, 1,8-dibromo-1-octyne and a copper halide as the catalyst are dissolved in tetrahydrofuran in a reaction vessel to form a reaction mixture, into which the above prepared Grignard reagent in tetrahydrofuran is added dropwise to effect the reaction between the reactants followed by hydrolysis and distillation to give 1-bromohexadeca-11-en-7-yne. The reaction is expressed by the following reaction equation:

Workup

  1. customto form a reaction mixture
  2. additionis added dropwise
  3. customthe reaction between the reactants
  4. customfollowed by hydrolysis and distillation

Sources & evidence

ORD record
ord-d6e76ae3c9aa4b879d64848b41ad20b4
Source dataset
uspto-grants-1983_07
Patent number
US04391984

Reaction notes

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