Dimethylformamide dimethyl acetal → HCID 54468687, compound

HRID 1074597Notes

Reaction equation

HRID 1074597 reaction equation
[Cl:1][C:2]1[CH:13]=[CH:12][CH:11]=[CH:10][C:3]=1[NH:4][C:5](=[O:9])[CH2:6][C:7]#[N:8].CO[CH:16](OC)[N:17]([CH3:19])[CH3:18]>>[Cl:1][C:2]1[CH:13]=[CH:12][CH:11]=[CH:10][C:3]=1[NH:4][C:5](=[O:9])[C:6]([C:7]#[N:8])=[CH:16][N:17]([CH3:18])[CH3:19]

Participants

3

Reactant 2

HCID 78373Dimethylformamide dimethyl acetalHCID 693035N-(2-chlorophenyl)-2-cyanoacetamide

Product 1

HCID 54468687HCID 54468687, compound

Procedure

As for Example 1, 2'-chloro-2-cyanoacetanilide, white crystalline product, m.p. 122.5°-123° C. (prepared as described in U.S. Pat. No. 3,116,312), is heated with N,N-dimethylformamide dimethylacetal to give 2'-chloro-2-cyano-3-dimethylaminoacrylanilide as colorless prisms, m.p. 104°-105° C.

Sources & evidence

ORD record
ord-0e889a84c7b841bf9ba7a4acf16e03fa
Source dataset
uspto-grants-1983_07
Patent number
US04393217

Reaction notes

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