反应详情

To the crude acetate prepared in Example 8 was added 10 g of p-toluenesulfonic acid monohydrate and then dropwise, over a period of 2 hours, 815 g (11.3 moles) of ethyl vinyl ether. The reaction was midly exothermic and the temperature was maintained at 35°-37° C. by occasional cooling. After the addition was complete, the reaction mixture was heated at 35°-40° C. for 16 hours. The crude material was used in the subsequent step.

1. temperaturethe temperature was maintained at 35°-37° C. by occasional cooling
2. additionAfter the addition
3. temperaturethe reaction mixture was heated at 35°-40° C. for 16 hours