Formaldehyde → HCID 131721227, compound

HRID 1075489Notes

Reaction equation

HRID 1075489 reaction equation
[C:1](#[N:7])[CH:2]([CH2:4][C:5]#[N:6])[OH:3].[C:8]([O-:11])(=O)C.[K+].[CH2:13]=[O:14]>C(O)(=O)C>[CH2:13]([C:4]([CH2:8][OH:11])([C:5]#[N:6])[CH:2]([OH:3])[C:1]#[N:7])[OH:14]

Participants

5

Reactant 3

HCID 712FormaldehydeHCID 517044Potassium AcetateHCID 212535622-Hydroxybutanedinitrile

Product 1

HCID 131721227HCID 131721227, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

It is also known that malonitrile can be reacted in glacial acetic acid, in the presence of potassium acetate, with gaseous formaldehyde at 100° C. to produce bis(methylol) malonitrile (Ardis, A. E.; Averill, S. J.; Gilbert, H.; Miller, F. F.; Schmidt, R. F.; Stewart, F. D.; and Trumbull, H. L.; J. Am. Chem. Soc., 72 (1950), 1305), although the yield is only 24% of the theoretical yield.

Sources & evidence

ORD record
ord-69fcaf08fbee4c609825c45931acf952
Source dataset
uspto-grants-1999_05
Patent number
US05902896

Reaction notes

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