Hydrochloric Acid → 2-[[5-fluoro-2-[3-methyl-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]-N-propan-2-ylbenzamide
Reaction equation
[CH3:23][c:24]1[cH:25][c:26]([NH2:27])[cH:28][cH:29][c:30]1[N:31]1[CH2:32][CH2:33][N:34]([CH3:37])[CH2:35][CH2:36]1.[CH:38]([OH:39])([CH3:40])[CH3:41].[Cl:1][c:2]1[n:3][cH:4][c:5]([F:21])[c:6]([NH:8][c:9]2[c:10]([C:11](=[O:12])[NH:13][CH:14]([CH3:15])[CH3:16])[cH:17][cH:18][cH:19][cH:20]2)[n:7]1.[ClH:22]>>[c:2]1([NH:27][c:26]2[cH:25][c:24]([CH3:23])[c:30]([N:31]3[CH2:32][CH2:33][N:34]([CH3:37])[CH2:35][CH2:36]3)[cH:29][cH:28]2)[n:3][cH:4][c:5]([F:21])[c:6]([NH:8][c:9]2[c:10]([C:11](=[O:12])[NH:13][CH:14]([CH3:15])[CH3:16])[cH:17][cH:18][cH:19][cH:20]2)[n:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-884e3f98560e476f9f1781e18daf56fc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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