Hydrochloric Acid → 2-methoxy-N-methyl-3-morpholino-2-(2-pyridyl)thiopropanamide hydrochloride

HRID 1076381Notes

Reaction equation

HRID 1076381 reaction equation
[CH3:1][O:2][C:3]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=1)([CH2:8][N:9]1[CH2:14][CH2:13][O:12][CH2:11][CH2:10]1)[C:4]([NH:6][CH3:7])=[S:5].[ClH:21]>CCOCC>[ClH:21].[CH3:1][O:2][C:3]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=1)([CH2:8][N:9]1[CH2:10][CH2:11][O:12][CH2:13][CH2:14]1)[C:4]([NH:6][CH3:7])=[S:5]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 538460772-methoxy-N-methyl-3-morpholino-2-(2-pyridyl)thiopropanamide

Product 1

HCID 867331962-methoxy-N-methyl-3-morpholino-2-(2-pyridyl)thiopropanamide hydrochloride

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

One gram of 2-methoxy-N-methyl-3-morpholino-2-(2-pyridyl)thiopropanamide in ether is added to ethereal hydrogen chloride. The resulting precipitate is filtered off and recrystallized from ethanol/ether to give 2-methoxy-N-methyl-3-morpholino-2-(2-pyridyl)thiopropanamide hydrochloride.

Workup

  1. filtrationThe resulting precipitate is filtered off
  2. customrecrystallized from ethanol/ether

Sources & evidence

ORD record
ord-5528fe86ee8040759f77d6552ca2b1b2
Source dataset
uspto-grants-1976_05
Patent number
US03956494

Reaction notes

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