反应详情

A quantity of 5 ml of methoxymethyl isocyanate was caused to react with 5 grams of 4-oximino-5-methyl-1,3-oxathiolane dissolved in 100 ml of anhydrous ether containing 10 drops of triethylamine over a period of 48 hours at room temperature. Conventional workup and recrystallization from isopropyl ether/ethyl acetate afforded 5.5 grams of product, mp 78°-79°; structure confirmed by spectral analysis.

1. customConventional workup and recrystallization from isopropyl ether/ethyl acetate