Piperidine → HCID 54142473, compound

HRID 1076695Notes

Reaction equation

HRID 1076695 reaction equation
[CH2:1]1[CH2:11][C:9](=[O:10])[C:8]2[C:3](=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH2:2]1.[N:12]1[CH:17]=[CH:16][C:15]([CH:18]=O)=[CH:14][CH:13]=1.N1CCCC[CH2:21]1>C(O)(=O)C>[N:12]1[CH:17]=[CH:16][C:15]([CH:18]=[C:11]2[CH2:1][CH:2]([CH3:21])[C:3]3[C:8](=[CH:7][CH:6]=[CH:5][CH:4]=3)[C:9]2=[O:10])=[CH:14][CH:13]=1

Participants

5

Reactant 3

HCID 8082PiperidineHCID 107241-TetraloneHCID 133894-Pyridinecarboxaldehyde

Product 1

HCID 54142473HCID 54142473, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A mixture of 80.0 grams (0.50 moles) of α-tetralone, 64.2 grams (0.60 moles) of 4 -pyridinecarboxaldehyde, 10 grams of piperidine and 10 grams of acetic acid are heated at 80° for 19 hours. The resultant solid is crystallized from about 400 ml. of ethanol to give 2-(4-pyridylmethylene)-3,4-dihydro-4-methyl-1(2H)-napthalenone.

Workup

  1. temperatureare heated at 80° for 19 hours
  2. customThe resultant solid is crystallized from about 400 ml

Sources & evidence

ORD record
ord-bfd00265e29d45da8efbbd70e59ac2ae
Source dataset
uspto-grants-1976_05
Patent number
US03957816

Reaction notes

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