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HRID1076864

反应详情

EQUATION

反应方程式

HRID 1076864 的结构方程式

REACTANTS

反应物

3
结构：CCOC(=O)C(C#N)=Cc1ccccc1
HCID74845

2-Cyano-3-phenylacrylic acid ethyl ester

C12H11NO2

结构：CC[O-].[Na+]
HCID2723922

Ethanol, sodium salt

C2H5NaO

结构：CC(C)OC(=O)CC(=N)N
HCID12391080

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)C1=C(N)NC(N)=C(C(=O)OC(C)C)C1c1ccccc1
HCID70631841

未命名化合物

收率 54%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

Upon heating a solution of 10.1 g benzylidenecyanoacetic acid ethyl ester, 7.2 g amidinoacetic acid isopropyl ester and 0.6 g sodium ethylate in 150 ml ethanol for 4 hours, 2,6-diamino-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylic acid 3-ethyl ester 5-isopropyl ester of m.p. 170° is obtained. Yield: 54% of theory.