Acetone → HCID 22484390, compound

HRID 1076949Notes

Reaction equation

HRID 1076949 reaction equation
[C:1]([OH:10])(=[O:9])[C@@H:2]([C@H:4]([C:6]([OH:8])=[O:7])[OH:5])[OH:3].CC(C)=[O:13]>O>[C:6]([CH:4]([CH:2]([C:1]([O-:10])=[O:9])[OH:3])[OH:5])([O-:8])=[O:7].[OH2:13]

Participants

4

Reactant 2

HCID 180AcetoneHCID 444305L-Tartaric acid

Product 1

HCID 22484390HCID 22484390, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

In 50 volume parts of water are dissolved 19.0 parts of TRH. H2O and 7.5 parts of L-tartaric acid, followed by the addition of 700 volume parts of acetone. The resultant oil is rubbed with a glass rod and the crystals formed are recovered by filtration, washed with hot ethanol and dried under reduced pressure. The described procedure yields 24.5 parts of TRH tartrate-water as crystals melting at 127°C-129°C. [α]D25 =-49.45° (c=1.0 in water)

Workup

  1. customthe crystals formed
  2. filtrationare recovered by filtration
  3. washwashed with hot ethanol
  4. customdried under reduced pressure

Sources & evidence

ORD record
ord-c997eaf9c7374f3a91e99b392a3ddb06
Source dataset
uspto-grants-1976_05
Patent number
US03959247

Reaction notes

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