HRID1077598

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6422

未命名化合物

结构：CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CN(C(C)(C)C)C4=CC(=O)C=C[C@]4(C)[C@H]3CC[C@]12CC(=O)O

HCID86749711

未命名化合物

PRODUCTS

生成物

结构：CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=CC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C

HCID10429262

未命名化合物

PROCEDURE

实验过程

A sample of 17β-N,N-diethylcarbamoyl-6-t-butylcarboxy-6-azaandrost-1,4-dien-3-one (188 mg, 0.400 mmol), prepared in part B above, is treated with trifluoroacetic acid as described in Example 4 above to give, after trituration with diethyl ether/hexanes 17β-N,N-diethylcarbamoyl-6-azaandrost-1,4-dien-3-one as a pale yellow solid; yield: 98 mg (66%); m.p.>250° C. Anal. Calcd. for C23H34N2O2 ·1/2H2O; C, 72.78; H, 9.29; N, 7.38. Found: C, 72.89; H, 9.20; N, 7.43.

WORKUP

后处理

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