Phthalic Anhydride → HCID 19698913, compound

HRID 1077600Notes

Reaction equation

HRID 1077600 reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH:8](NC)[CH3:9].[C:12]1(=[O:22])[O:17][C:15](=O)[C:14]2=[CH:18][CH:19]=[CH:20][CH:21]=[C:13]12.[CH2:23]([N:25](CC)CC)C>C1(C)C=CC=CC=1>[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH:8]([CH3:9])[CH2:23][N:25]1[C:12](=[O:22])[C:13]2=[CH:21][CH:20]=[CH:19][CH:18]=[C:14]2[C:15]1=[O:17]

Participants

5

Reactant 3

HCID 6811Phthalic AnhydrideHCID 8471TriethylamineHCID 19698939HCID 19698939, compound

Product 1

HCID 19698913HCID 19698913, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

8-Bromo-2-methylaminooctane is treated with phthalic anhydride in toluene in the presence of triethylamine under reflux. The solvent is removed in vacuo. The residue, when triturated with water, acidified with hydrochloric acid and crystallized from alcohol will yield N-(8-bromo-2-methyloctyl)phthalimide.

Workup

  1. temperatureunder reflux
  2. customThe solvent is removed in vacuo
  3. customThe residue, when triturated with water
  4. customcrystallized from alcohol

Sources & evidence

ORD record
ord-cc22abfff38d4a1494e483a29d71a742
Source dataset
uspto-grants-1996_08
Patent number
US05543507

Reaction notes

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