HCID 178444430, compound → HCID 178444429, compound

HRID 1078170Notes

Reaction equation

HRID 1078170 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([Mg]Br)[CH:5]=[CH:6][C:7]=1[F:8].Cl[SiH:12]1[CH2:17][CH2:16][CH:15]([CH2:18][CH2:19][C@H:20]2[CH2:25][CH2:24][C@H:23]([CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH2:22][CH2:21]2)[CH2:14][CH2:13]1>C1COCC1>[F:1][C:2]1[CH:3]=[C:4]([SiH:12]2[CH2:17][CH2:16][CH:15]([CH2:18][CH2:19][C@H:20]3[CH2:21][CH2:22][C@H:23]([CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH2:24][CH2:25]3)[CH2:14][CH2:13]2)[CH:5]=[CH:6][C:7]=1[F:8]

Participants

4

Reactant 2

HCID 178444430HCID 178444430, compoundHCID 178505835HCID 178505835, compound

Product 1

HCID 178444429HCID 178444429, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

A 15 ml THF solution of 1.0M 3,4-difluorophenylmagnesium bromide (15 mmol) was dripped into a mixed solution of 2.5 g (7.9 mmol) of 1-chloro-4-(2-(trans-4-n-pentylcyclohexyl) ethyl)-1-silacyclohexane and 50 ml of THF.

Sources & evidence

ORD record
ord-d8f4139ed86d4da68763b0d4de5629fe
Source dataset
uspto-grants-1996_08
Patent number
US05547606

Reaction notes

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