Piperidine → HCID 19429657, compound

HRID 1078312Notes

Reaction equation

HRID 1078312 reaction equation
Cl[C:2]1[C:3]2[CH:13]=[CH:12][C:11]([Cl:14])=[CH:10][C:4]=2[S:5](=[O:9])(=[O:8])[C:6]=1[CH3:7].[NH:15]1[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1>O>[Cl:14][C:11]1[CH:12]=[CH:13][C:3]2[CH:2]=[C:6]([CH2:7][N:15]3[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]3)[S:5](=[O:9])(=[O:8])[C:4]=2[CH:10]=1

Participants

4

Reactant 2

HCID 8082PiperidineHCID 676224HCID 676224, compound

Product 1

HCID 19429657HCID 19429657, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
80 °C

Procedure

A mixture of 3.75 g 3,6-dichloro-2-methyl-benzo[b]-thiophene-1,1-dioxide and 35 ml piperidine is stirred for 4 hours at 80° C., water is subsequently added and it is extracted with ethyl acetate. The extract is concentrated by evaporation and it is ground with ethyl acetate. 1.6 g of the title compound (36% of the theoretical yield) of melting point 154°-156° C. is isolated.

Workup

  1. extractionit is extracted with ethyl acetate
  2. concentrationThe extract is concentrated by evaporation and it

Sources & evidence

ORD record
ord-e4c21e0384394d27814f7172c0de03ad
Source dataset
uspto-grants-1996_08
Patent number
US05547980

Reaction notes

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