HCID 19429426, compound → HCID 19429438, compound

HRID 1078389Notes

Reaction equation

HRID 1078389 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([NH:11][C:12](=O)[CH2:13][CH2:14][CH2:15][CH2:16][N:17]2[CH:21]=[CH:20][N:19]=[CH:18]2)([CH3:10])[CH3:9])=[CH:4][CH:3]=1>C1COCC1>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([NH:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][N:17]2[CH:21]=[CH:20][N:19]=[CH:18]2)([CH3:10])[CH3:9])=[CH:4][CH:3]=1

Participants

3

Reactant 1

HCID 19429426HCID 19429426, compound

Product 1

HCID 19429438HCID 19429438, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

In a similar manner to Example 52d, a solution of N-[1-(4-chlorophenyl)-1-methylethyl]-5-(imidazol-1-yl)pentanamide (5.1 g) in THF (125 ml) was reduced with BH3 /THF (63.7 ml of a 1M solution) to give N-[1-(4-chlorophenyl)-1-methylethyl]-5-(imidazol-1-yl)pentylamine as an oil, b.p. 195° C. (0.05 mmHg).

Sources & evidence

ORD record
ord-60f8fe1c1f9940bdbc92377400312576
Source dataset
uspto-grants-1996_08
Patent number
US05547972

Reaction notes

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