Hydrochloric Acid → HCID 9863252, compound

HRID 1078395Notes

Reaction equation

HRID 1078395 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([NH:11][CH2:12][CH2:13][CH2:14][N:15]2[CH:19]=[CH:18][N:17]=[CH:16]2)([CH3:10])[CH3:9])=[CH:4][CH:3]=1.[ClH:20]>CCOCC>[ClH:1].[ClH:20].[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([NH:11][CH2:12][CH2:13][CH2:14][N:15]2[CH:19]=[CH:18][N:17]=[CH:16]2)([CH3:10])[CH3:9])=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 9863253HCID 9863253, compound

Product 1

HCID 9863252HCID 9863252, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Ex 68b N-[1-(4-Chlorophenyl)-1-methylethyl]-3-(imidazol-1-yl)propylamine as an oil, b.p. 180° C. (0.05 mmHg) [Example 68(1)]. A sample of this oil was dissolved in ether and ethereal hydrogen chloride added. The solid obtained was collected by filtration, dried and recrystallised from propan-2-ol to give N-[1-(4-chlorophenyl)-1-methylethyl]-3-(imidazol-1-yl)propylamine dihydrochloride, m.p. 216°-218° C. [Example 68(2)].

Workup

  1. customThe solid obtained
  2. filtrationwas collected by filtration
  3. customdried
  4. customrecrystallised from propan-2-ol

Sources & evidence

ORD record
ord-c9ac588cd6d7412083b13749ff06b357
Source dataset
uspto-grants-1996_08
Patent number
US05547972

Reaction notes

Loading…