Isopropanol → HCID 23196166, compound

HRID 1078577Notes

Reaction equation

HRID 1078577 reaction equation
[CH3:1][O:2][C:3]1[C:4]([O:15][CH3:16])=[CH:5][C:6]2[O:11][C:10](=[O:12])[CH:9]=[C:8]([CH3:13])[C:7]=2[CH:14]=1.[C:17]1([N:23]2[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]2)[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1.[CH:29](O)(C)[CH3:30]>>[CH3:1][O:2][C:3]1[C:4]([O:15][CH3:16])=[CH:5][C:6]2[O:11][C:10](=[O:12])[C:9]([CH2:29][CH2:30][N:26]3[CH2:27][CH2:28][N:23]([C:17]4[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=4)[CH2:24][CH2:25]3)=[C:8]([CH3:13])[C:7]=2[CH:14]=1

Participants

4

Reactant 3

HCID 3776IsopropanolHCID 70961-PhenylpiperazineHCID 779666,7-Dimethoxy-4-methylcoumarin

Product 1

HCID 23196166HCID 23196166, compoundYield 43%

Procedure

Process B; starting materials: 3-[2-methanesulphonyloxy)ethyl]-6,7-dimethoxy-4-methyl-2H-1-benzopyran-2-one (Example 28) and 1-phenylpiperazine; yield 43%; m.p. 169°-172° C. (from isopropanol).

Sources & evidence

ORD record
ord-fd88e9a5ed124e3d94826c108430ee66
Source dataset
uspto-grants-1996_08
Patent number
US05550129

Reaction notes

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