Sodium → HCID 54524162, compound

HRID 1079347Notes

Reaction equation

HRID 1079347 reaction equation
[C:1]1(=[O:33])[N:5]([C@@H:6]2[C@@H:14]([O:15]C(=O)C)[C@H:13]([O:19]C(=O)C)[C@@H:12]([CH2:23][O:24]C(=O)C)[O:11][C@H:7]2[O:8][CH2:9][CH3:10])[C:4](=[O:28])[C:3]2=[CH:29][CH:30]=[CH:31][CH:32]=[C:2]12.[Na]>CO>[C:4]1(=[O:28])[N:5]([C@@H:6]2[C@@H:14]([OH:15])[C@H:13]([OH:19])[C@@H:12]([CH2:23][OH:24])[O:11][C@H:7]2[O:8][CH2:9][CH3:10])[C:1](=[O:33])[C:2]2=[CH:32][CH:31]=[CH:30][CH:29]=[C:3]12

Participants

4

Reactant 2

HCID 5360545SodiumHCID 54152158HCID 54152158, compound

Product 1

HCID 54524162HCID 54524162, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Ethyl 2-deoxy-2-phthalamido-3,4,6-tri-O-acetyl-β-D-glucopyranosyide (compound 13) from example 17 was taken up in 100 mL of dry methanol and treated with 100 mg of sodium metal. The solution was stirred at room temperature for 24 hours and then neutralized with Amberlite [R-120(H+)] resin, filtered, and evaporated to dryness in vacuo. This compound was used in the preparation of compound 15 and compound 66.

Workup

  1. filtrationfiltered
  2. customevaporated to dryness in vacuo
  3. customThis compound was used in the preparation of compound 15 and compound 66

Sources & evidence

ORD record
ord-c9fa56c8c2314ddeae119e0eed98b77c
Source dataset
uspto-grants-1996_12
Patent number
US05580858

Reaction notes

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