Ammonium → 1-acetyl-3-trifluoromethyl-5,6-dihydro-8H-imidazo[1,5-a]pyrazine-7-carboxylic acid tert-butyl ester
Reaction equation
[Br-:27].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[n:11]([c:14]([C:23]([F:24])([F:25])[F:26])[n:15][c:16]2[C:17]([N:18]([O:19][CH3:20])[CH3:21])=[O:22])[CH2:12][CH2:13]1.[CH3:28][Mg+:29].[Cl-:30].[NH4+:31].[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[n:11]([c:14]([C:23]([F:24])([F:25])[F:26])[n:15][c:16]2[C:17](=[O:22])[CH3:28])[CH2:12][CH2:13]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-e0a09f9896a544b88e13d969a1d38ea2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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